Pyrimidine-based inhibitors of dynamin I GTPase activity: competitive inhibition at the pleckstrin homology domain
- Creator: Odell, Luke R. , Abdel-Hamid, Mohammed K. , McCluskey, Adam , Hill, Timothy A. , Chau, Ngoc , Young, Kelly A. , Deane, Fiona M. , Sakoff, Jennette A. , Andersson, Sofia , Daniel, James A. , Robinson, Phillip J.
- Resource Type: journal article
- Date: 2017
A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells
- Creator: Stehn, Justine R. , Haass, Nikolas K. , Allanson, Munif , Fath, Thomas , Hill, Timothy A. , McCluskey, Adam , Schevzov, Galina , Palmer, Stephen J. , Hardeman, Edna C. , Winlaw, David , Reeve, Vivienne E. , Dixon, Ian , Bonello, Teresa , Weninger, Wolfgang , Cripe, Timothy P. , Gunning, Peter W. , Desouza, Melissa , Kottyan, Gregg , Treutlein, Herbert , Zeng, Jun , Nascimento, Paula R. B. B. , Sequeira, Vanessa B. , Butler, Tanya L.
- Resource Type: journal article
- Date: 2013
Pyrimidyn compounds: dual-action small molecule pyrimidine-based dynamin inhibitors
- Creator: McGeachie, Andrew B. , Odell, Luke R. , Mariana, Anna , Whiting, Ainslie , Perera, Swetha , Novelle, Aimee , Young, Kelly A. , Deane, Fiona M. , Gilbert, Jayne , Sakoff, Jennette A. , Chircop, Megan , McCluskey, Adam , Quan, Annie , Robinson, Phillip J. , Daniel, James A. , Chau, Ngoc , Hill, Timothy A. , Gorgani, Nick N. , Keating, Damien J. , Cousin, Michael A. , van Dam, Ellen M.
- Resource Type: journal article
- Date: 2013
An Ugi-intramolecular Diels-Alder route to highly substituted tetrahydroepoxyisoindole carboxamides
- Creator: Gordon, Christopher P. , Young, Kelly A. , Robertson, Mark J. , Hill, Timothy A. , McCluskey, Adam
- Resource Type: journal article
- Date: 2011
Iminochromene inhibitors of Dynamins I and II GTPase activity and Endocytosis
- Creator: Hill, Timothy A. , Mariana, Anna , McCluskey, Adam , Gordon, Christopher P. , Odell, Luke R. , Robertson, Mark J. , McGeachie, Andrew B. , Chau, Ngoc , Daniel, James A. , Gorgani, Nick N. , Robinson, Phillip J.
- Resource Type: journal article
- Date: 2010
The antiplasmodial activity of norcantharidin analogs
- Creator: Bajsa, Joanna , McCluskey, Adam , Gordon, Christopher P. , Stewart, Scott G. , Hill, Timothy A. , Sahu, Rajnish , Duke, Stephen O. , Tekwani, Babu L.
- Resource Type: journal article
- Date: 2010
Inhibition of dynamin mediated endocytosis by the dynoles-synthesis and functional activity of a family of indoles
- Creator: Hill, Timothy A. , Gordon, Christopher P. , Robinson, Phillip J. , McCluskey, Adam , McGeachie, Andrew B. , Venn-Brown, Barbara , Odell, Luke R. , Chau, Ngoc , Quan, Annie , Mariana, Anna , Sakoff, Jennette A. , Chircop, Megan
- Resource Type: journal article
- Date: 2009
Norcantharidin analogues: synthesis, anticancer activity and protein phosphatase 1 and 2A inhibition
- Creator: Hill, Timothy A. , Stewart, Scott G. , Gordon, Christopher P. , Ackland, Stephen P. , Gilbert, Jayne , Sauer, Benjamin , Sakoff, Jennette A. , McCluskey, Adam
- Resource Type: journal article
- Date: 2008
Heterocyclic substituted cantharidin and norcantharidin analogues-synthesis, protein phosphatase (1 and 2A) inhibition, and anti-cancer activity
- Creator: Hill, Timothy A. , Stewart, Scott G. , Sauer, Benjamin , Gilbert, Jayne , Ackland, Stephen P. , Sakoff, Jennette A. , McCluskey, Adam
- Resource Type: journal article
- Date: 2007
Norcantharimides, synthesis and anticancer activity: synthesis of new norcantharidin analogues and their anticancer evaluation
- Creator: Hill, Timothy A. , Stewart, Scott G. , Ackland, Stephen P. , Gilbert, Jayne , Sauer, Benjamin , Sakoff, Jennette A. , McCluskey, Adam
- Resource Type: journal article
- Date: 2007
Synthesis and biological evaluation of norcantharidin analogues: towards PP1 selectivity
- Creator: Stewart, Scott G. , Hill, Timothy A. , Gilbert, Jayne , Ackland, Stephen P. , Sakoff, Jennette A. , McCluskey, Adam
- Resource Type: journal article
- Date: 2007
BiCl3-mediated opening of epoxides, a facile route to chlorohydrins or amino alcohols: one reagent, two paths
- Creator: McCluskey, Adam , Leitch, Sarah K. , Garner, James , Caden, Christine E. , Hill, Timothy A. , Odell, Luke R. , Stewart, Scott G.
- Resource Type: journal article
- Date: 2005
Parallel solution-phase synthesis of targeted tyrphostin libraries with anticancer activity
- Creator: Hill, Timothy A. , Sakoff, Jennette A. , Robinson, Phillip J. , McCluskey, Adam
- Resource Type: journal article
- Date: 2005
Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity
- Creator: Hill, Timothy A. , Odell, Luke R. , Quan, Annie , Abagyan, Ruben , Ferguson, Gemma , Robinson, Phillip J. , McCluskey, Adam
- Resource Type: journal article
- Date: 2004